Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 2/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010472 | 1.00 | MAOA (0.50) | MAOAKDM4EALDH1A1GAAMAPT | |
| SCHEMBL1009901 | 0.85 | MAOA (0.50) | MAOAKDM4EALDH1A1GAAMAPT | |
| SCHEMBL1009906 | 0.81 | MAOA (0.53) | MAOAKDM4EALDH1A1GAAMAPT | |
| SCHEMBL1009165 | 0.78 | MAOA (0.50) | MAOAKDM4EALDH1A1GAAMAPT | |
| SCHEMBL1011035 | 0.78 | MAOA (0.50) | MAOAKDM4EALDH1A1GAAMAPT | |
| SCHEMBL7993632 | 0.78 | MAOA (0.50) | MAOAKDM4EALDH1A1GAAMAPT | |
| SCHEMBL29405492 | 0.78 | MAOA (0.50) | MAOAKDM4EALDH1A1GAAMAPT | |
| SCHEMBL1010841 | 0.77 | PARP1 (0.46) | MAOAKDM4EALDH1A1GAAMAPT | |
| SCHEMBL625670 | 0.77 | MAOA (0.58) | MAOAKDM4EALDH1A1GAAMAPT | |
| SCHEMBL19862022 | 0.76 | MAPK10 (0.46) | MAOAKDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111417635-B | Pyrazolopyrimidines with anti-Respiratory Syncytial Virus (RSV) activity | 爱尔兰詹森科学公司 | 2024-01-02 | — | — | CN | disclosed |