Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.46 |
| ▸ | NPY4R | P50391 | 8/20 | 0.46 |
| ▸ | NPY1R | P25929 | 6/20 | 0.46 |
| ▸ | NPY2R | P49146 | 4/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | IL1RN | P18510 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30656916 | 0.95 | MMP1 (0.48) | MMP1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30400489 | 0.93 | NPY4R (0.52) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL29705780 | 0.89 | OPRD1 (0.54) | NPY4RNPY1RNPY2ROPRM1OPRD1 | |
| SCHEMBL30034864 | 0.87 | NPY1R (0.53) | NPY4RNPY1RNPY2ROPRM1OPRD1 | |
| SCHEMBL29587542 | 0.86 | OPRD1 (0.52) | OPRM1OPRD1 | |
| SCHEMBL29815391 | 0.85 | NPY4R (0.51) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL31553196 | 0.85 | YARS1 (0.46) | NPY4RNPY1RNPY2ROPRM1OPRD1 | |
| SCHEMBL30729668 | 0.85 | FOLH1 (0.53) | NPY4RNPY1RNPY2ROPRM1OPRD1 | |
| SCHEMBL30729665 | 0.85 | FOLH1 (0.53) | NPY4RNPY1RNPY2ROPRM1OPRD1 | |
| SCHEMBL31345046 | 0.85 | BACE1 (0.53) | NPY4RNPY1RNPY2RNPY5RIL1RN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357320-A1 | HELICAL STAPLED PEPTIDES AND USES THEREOF | PARABILIS MEDICINES, INC. | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357320-A1 | HELICAL STAPLED PEPTIDES AND USES THEREOF | ESRRB, ESR1, ESRRA | MMP1 1199/4885NPY4R 59/4885NPY1R 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.