Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26639845 | 1.00 | QDPR (0.41) | QDPRSLC6A4PIK3CDPIK3R1PIK3CA | |
| Formic Acid SCHEMBL30657455 | 0.95 | QDPR (0.38) | QDPRSLC6A4PIK3CDPIK3R1PIK3CA | |
| SCHEMBL26639807 | 0.83 | QDPR (0.34) | QDPRSLC6A4PIK3CDPIK3R1PIK3CA | |
| SCHEMBL26639939 | 0.73 | QDPR (0.38) | QDPRPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30657462 | 0.72 | HRH4 (0.41) | — | |
| SCHEMBL26639919 | 0.72 | HRH4 (0.41) | — | |
| SCHEMBL30657485 | 0.68 | MEN1 (0.34) | — | |
| SCHEMBL26639760 | 0.68 | MEN1 (0.34) | — | |
| SCHEMBL30657478 | 0.68 | MEN1 (0.34) | — | |
| SCHEMBL26639820 | 0.68 | MEN1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215256-A1 | SOS1 INHIBITORS AND USES THEREOF | Revolution Medicines, Inc. (US) | 2023-11-09 | — | — | WO | disclosed |