Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26639760 | 1.00 | MEN1 (0.34) | MEN1KMT2AMAPTATMPDE5A | |
| SCHEMBL30657478 | 0.81 | MEN1 (0.34) | MEN1KMT2AMAPTPDE5A | |
| SCHEMBL26639820 | 0.81 | MEN1 (0.34) | MEN1KMT2AMAPTPDE5A | |
| SCHEMBL26639849 | 0.77 | PDE4A (0.31) | — | |
| SCHEMBL30657453 | 0.77 | PDE4A (0.31) | — | |
| SCHEMBL31364636 | 0.75 | ALDH1A1 (0.30) | KMT2A | |
| SCHEMBL19878145 | 0.73 | NQO2 (0.41) | MEN1KMT2AMAPTATMPDE5A | |
| SCHEMBL26639919 | 0.72 | HRH4 (0.41) | MEN1KMT2A | |
| SCHEMBL30657462 | 0.72 | HRH4 (0.41) | MEN1KMT2A | |
| SCHEMBL26639939 | 0.70 | QDPR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215256-A1 | SOS1 INHIBITORS AND USES THEREOF | Revolution Medicines, Inc. (US) | 2023-11-09 | — | — | WO | disclosed |