Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 3/20 | 0.40 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26639919 | 1.00 | HRH4 (0.41) | HRH4ACHEBACE1HTR3AUCHL3 | |
| SCHEMBL26639939 | 0.78 | QDPR (0.38) | HRH4ACHEBACE1 | |
| SCHEMBL26639845 | 0.72 | QDPR (0.41) | — | |
| SCHEMBL30657464 | 0.72 | QDPR (0.41) | — | |
| SCHEMBL30657478 | 0.72 | MEN1 (0.34) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL26639820 | 0.72 | MEN1 (0.34) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL30657485 | 0.72 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL26639760 | 0.72 | MEN1 (0.34) | MEN1KMT2A | |
| Formic Acid SCHEMBL30657455 | 0.69 | QDPR (0.38) | — | |
| SCHEMBL30657463 | 0.67 | QDPR (0.42) | ACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215256-A1 | SOS1 INHIBITORS AND USES THEREOF | Revolution Medicines, Inc. (US) | 2023-11-09 | — | — | WO | disclosed |