Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 5/20 | 0.41 |
| ▸ | NTSR2 | O95665 | 4/20 | 0.41 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | RAMP3 | O60896 | 2/20 | 0.40 |
| ▸ | CALCR | P30988 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | NPY4R | P50391 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30657496 | 0.97 | CALCRL (0.45) | F2TGM2TASP1CALCRLNPY1R | |
| SCHEMBL30657490 | 0.95 | CALCRL (0.43) | F2CALCRLNPY1RRAMP3CALCR | |
| SCHEMBL29726608 | 0.95 | CALCRL (0.44) | F2CALCRLNPY1RRAMP3CALCR | |
| SCHEMBL30657497 | 0.93 | CALCRL (0.44) | TGM2CALCRLABCB1 | |
| SCHEMBL31140791 | 0.87 | CALCRL (0.46) | F2CALCRLNPY1RRAMP3CALCR | |
| SCHEMBL29726644 | 0.87 | CALCRL (0.46) | F2CALCRLNPY1RRAMP3CALCR | |
| SCHEMBL30657495 | 0.86 | F2 (0.47) | F2CALCRLRAMP3CALCR | |
| SCHEMBL30657494 | 0.83 | CALCRL (0.51) | NTSR1NTSR2CALCRLNPY1RSORT1 | |
| SCHEMBL29946190 | 0.82 | GZMB (0.52) | F2TASP1NTSR1NTSR2NPY1R | |
| SCHEMBL2399597 | 0.81 | F2 (0.45) | F2NTSR1NTSR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118320091-A | Compositions of caspase inhibitors and methods of use thereof | 香港大学 | 2024-07-12 | — | — | CN | disclosed |
| EP-4397770-A1 | STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS | PreAnalytiX GmbH (CH) | 2024-07-10 | — | — | EP | disclosed |
| US-20240024405-A1 | COMPOSITIONS OF CASPASE INHIBITORS AND METHODS OF USE THEREOF | THE UNIVERSITY OF HONG KONG (CN) | 2024-01-25 | — | — | US | disclosed |
| EP-3401406-B1 | STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS | PREANALYTIX GMBH (CH) | 2023-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240024405-A1 | COMPOSITIONS OF CASPASE INHIBITORS AND METHODS OF USE THEREOF | CASP6, CASP1, CASP3 | F2 1847/4885TGM2 1542/4885TASP1 615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.