SCHEMBL30658171

SCHEMBL30658171

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ OPRK1 P41145 7/20 0.55
▸ OPRM1 P35372 3/20 0.55
▸ MME P08473 2/20 0.52
▸ NPY1R P25929 1/20 0.49
▸ NPY2R P49146 1/20 0.49
▸ NPY4R P50391 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29459545 0.93 OPRK1 (0.58) OPRK1OPRM1MMENPY1RNPY2R
SCHEMBL29808027 0.88 GNPAT (0.58) OPRK1OPRM1
SCHEMBL30073889 0.86 BACE1 (0.48) OPRK1OPRM1
SCHEMBL29380139 0.86 GHSR (0.54) OPRK1MME
SCHEMBL30388715 0.86 MME (0.56) MME
SCHEMBL2777114 0.86 OPRK1 (0.59) OPRK1NPY1RNPY2RNPY4R
SCHEMBL2777118 0.86 OPRK1 (0.59) OPRK1NPY1RNPY2RNPY4R
SCHEMBL31433322 0.85 MME (0.62) OPRM1MME
SCHEMBL30957128 0.84 OPRK1 (0.68) OPRK1OPRM1NPY1RNPY2RNPY4R
SCHEMBL31152919 0.84 OPRK1 (0.63) OPRK1OPRM1MMENPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12514937-B2 Methods for detecting CCR2 receptors WASHINGTON UNIVERSITY (US) 2026-01-06 — — US claimed
US-20240299598-A1 METHODS FOR DETECTING CCR2 RECEPTORS WASHINGTON UNIVERSITY (US) 2024-09-12 — — US claimed
US-12016935-B2 Methods for detecting CCR2 receptors WASHINGTON UNIVERSITY (US) 2024-06-25 — — US claimed
US-12514937-B2 Methods for detecting CCR2 receptors WASHINGTON UNIVERSITY (US) 2026-01-06 — — US disclosed
US-20240299598-A1 METHODS FOR DETECTING CCR2 RECEPTORS WASHINGTON UNIVERSITY (US) 2024-09-12 — — US disclosed
US-12016935-B2 Methods for detecting CCR2 receptors WASHINGTON UNIVERSITY (US) 2024-06-25 — — US disclosed
US-20230381349-A1 METHODS AND COMPOSITIONS FOR IMAGING AND TREATING CANCER WASHINGTON UNIVERSITY (US) 2023-11-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12016935-B2 Methods for detecting CCR2 receptors CCR2, CCR1, CCR5 OPRK1 236/4885OPRM1 270/4885MME 1386/4885
US-20240299598-A1 METHODS FOR DETECTING CCR2 RECEPTORS CCR2, CCR1, CCR5 OPRK1 236/4885OPRM1 270/4885MME 1386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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