Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | NCF1 | P14598 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30334261 | 0.81 | ROCK2 (0.36) | — | |
| SCHEMBL30658187 | 0.76 | ITGA2B (0.30) | ITGA2B | |
| SCHEMBL30658179 | 0.76 | EIF2AK4 (0.34) | HRH3 | |
| SCHEMBL30658182 | 0.73 | GABRA1 (0.37) | HRH3ALDH1A1 | |
| SCHEMBL31565730 | 0.71 | HRH3 (0.42) | HRH3 | |
| SCHEMBL15175908 | 0.71 | PLD1 (0.44) | HRH3PLD1ADRB2NCF1KDM4E | |
| SCHEMBL27008153 | 0.70 | DYRK1A (0.40) | ITGA2BHTR2CADRB2NCF1ADRB1 | |
| Hydrochloric Acid SCHEMBL23780886 | 0.70 | ADRB2 (0.42) | HRH3PLD1ADRB2NCF1KDM4E | |
| SCHEMBL27008174 | 0.68 | KCNH2 (0.40) | ITGA2BHTR2C | |
| SCHEMBL30658188 | 0.67 | SIGMAR1 (0.36) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308576-B1 | NEW THIAZOLOPYRIMIDINONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2025-04-23 | — | — | EP | disclosed |
| CN-116981674-A | Novel thiazolopyrimidinone derivatives | 豪夫迈·罗氏有限公司 | 2023-10-31 | — | — | CN | disclosed |