Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 8/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31442803 | 0.83 | JAK1 (0.54) | JAK1WDR5 | |
| SCHEMBL30659278 | 0.83 | JAK1 (0.54) | JAK1WDR5 | |
| SCHEMBL29430994 | 0.75 | JAK1 (0.47) | JAK1 | |
| SCHEMBL14144348 | 0.73 | ALDH1A1 (0.54) | TSHRMAPTMEN1KMT2ALMNA | |
| SCHEMBL31329758 | 0.72 | PTGDR2 (0.38) | PTGDR2JAK1TSHRWDR5MAPT | |
| SCHEMBL29650110 | 0.71 | LMNA (0.47) | TSHRMAPTMEN1KMT2ALMNA | |
| SCHEMBL29948559 | 0.71 | CNR1 (0.50) | MAPTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL9731949 | 0.71 | WDR5 (0.43) | JAK1WDR5MAPTLMNAPOLB | |
| SCHEMBL18129721 | 0.70 | PRKACA (0.56) | MAPT | |
| SCHEMBL31407903 | 0.70 | PDK4 (0.41) | JAK1TSHRMAPTLMNAJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536656-A1 | BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS | C4 Therapeutics, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| WO-2023239750-A1 | BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS | C4 THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |