Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 5/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320613 | 1.00 | ALDH1A1 (0.70) | ALDH1A1KMT2AMEN1TDP1TSHR | |
| Ammonia Solution, Strong SCHEMBL28716654 | 0.98 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1TDP1TSHR | |
| SCHEMBL11359633 | 0.83 | IAPP (0.53) | ALDH1A1KMT2AMEN1TDP1TSHR | |
| SCHEMBL96214 | 0.83 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1TDP1TSHR | |
| SCHEMBL311198 | 0.83 | ERN1 (0.54) | ALDH1A1KMT2AMEN1TDP1ERN1 | |
| SCHEMBL30541650 | 0.80 | ERN1 (0.52) | ALDH1A1KMT2AMEN1TDP1ERN1 | |
| SCHEMBL28806185 | 0.80 | ALDH1A1 (0.94) | ALDH1A1KMT2AMEN1TDP1TSHR | |
| Charcoal, Activated SCHEMBL29407959 | 0.80 | ERN1 (0.52) | ALDH1A1KMT2AMEN1TDP1ERN1 | |
| SCHEMBL29220003 | 0.80 | ERN1 (0.52) | ALDH1A1KMT2AMEN1TDP1ERN1 | |
| Hydrogen Sulfide SCHEMBL28185526 | 0.80 | ALDH1A1 (0.94) | ALDH1A1KMT2AMEN1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12576156-B2 | Compound comprising self-immolative group and ligand-drug conjugate comprising same | TRIOAR, INC. (KR) | 2026-03-17 | — | — | US | disclosed |
| EP-4545096-A1 | COMPOUND COMPRISING SELF-IMMOLATIVE GROUP AND LIGAND-DRUG CONJUGATE COMPRISING SAME | Trioar, Inc. (KR) | 2025-04-30 | — | — | EP | disclosed |
| EP-4545097-A1 | NOVEL LINKER COMPOUND AND LIGAND-DRUG CONJUGATE THEREFOR | Trioar, Inc. (KR) | 2025-04-30 | — | — | EP | disclosed |
| US-20250121072-A1 | COMPOUND COMPRISING SELF-IMMOLATIVE GROUP AND LIGAND-DRUG CONJUGATE COMPRISING SAME | TRIOAR, INC. (KR) | 2025-04-17 | — | — | US | disclosed |
| CN-119522110-A | Novel linker compounds and ligand-drug conjugates thereof | 特里奥尔株式会社 | 2025-02-25 | — | — | CN | disclosed |
| CN-119451701-A | Compounds comprising self-destructing groups and ligand-drug conjugates comprising the same | 特里奥尔株式会社 | 2025-02-14 | — | — | CN | disclosed |
| WO-2024005461-A1 | NOVEL LINKER COMPOUND AND LIGAND-DRUG CONJUGATE THEREFOR | 주식회사 트리오어 | 2024-01-04 | — | — | WO | disclosed |
| WO-2024005460-A1 | COMPOUND COMPRISING SELF-IMMOLATIVE GROUP AND LIGAND-DRUG CONJUGATE COMPRISING SAME | 주식회사 트리오어 | 2024-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12576156-B2 | Compound comprising self-immolative group and ligand-drug conjugate comprising same | SLC7A1, CLTC, MSR1 | ALDH1A1 347/4885KMT2A 1653/4885MEN1 1963/4885 |
| US-20250121072-A1 | COMPOUND COMPRISING SELF-IMMOLATIVE GROUP AND LIGAND-DRUG CONJUGATE COMPRISING SAME | CD44, MSN, EPCAM | ALDH1A1 361/4885KMT2A 3854/4885MEN1 1712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.