Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30665277 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2HPGDALDH1A1HSD17B10LMNA | |
| Benzoic Acid SCHEMBL9928995 | 0.76 | DAO (0.44) | SMN1; SMN2ALDH1A1HSD17B10LMNAPOLB | |
| SCHEMBL31188529 | 0.73 | GAA (0.60) | SMN1; SMN2HPGDALDH1A1LMNAPOLB | |
| SCHEMBL2711084 | 0.71 | NPC1 (0.58) | HPGDALDH1A1HSD17B10LMNAPOLB | |
| SCHEMBL18495300 | 0.71 | HPGD (0.51) | SMN1; SMN2HPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL7080320 | 0.71 | MAPT (0.73) | SMN1; SMN2ALDH1A1HSD17B10POLBMAPK10 | |
| SCHEMBL21805809 | 0.71 | ALDH1A1 (0.59) | SMN1; SMN2HPGDALDH1A1LMNAPOLB | |
| SCHEMBL31188605 | 0.70 | TAAR1 (0.55) | SMN1; SMN2ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL2660078 | 0.70 | GAA (0.49) | SMN1; SMN2HPGDALDH1A1ADORA1MAPK10 | |
| SCHEMBL30665247 | 0.70 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDALDH1A1LMNAADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532471-A2 | 4-(3H-PYRAZOLO[4,3-F]QUINOLIN-7-YL)-N-(2-(DIMETHYLAMINO)ETHYL)BENZAMIDE- OR HYDROXAMIC ACID COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Purdue Research Foundation (US) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023235837-A2 | 4-(3H-PYRAZOLO[4,3-F]QUINOLIN-7-YL)-N-(2-(DIMETHYLAMINO)ETHYL)BENZAMIDE- OR HYDROXAMIC ACID COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | PURDUE RESEARCH FOUNDATION (US) | 2023-12-07 | — | — | WO | disclosed |