Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.59 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31285 | 0.86 | HSD17B1 (0.51) | HSD17B1HSD17B2MAOBMAOAMAPT | |
| SCHEMBL30921 | 0.82 | HSD17B1 (0.73) | HSD17B1HSD17B2MAOBMAOAMAPT | |
| SCHEMBL23147 | 0.82 | HSD17B1 (0.67) | HSD17B1HSD17B2MAOBMAOAMAPT | |
| SCHEMBL31420 | 0.81 | HSD17B1 (0.64) | HSD17B1HSD17B2MAOBMAOAMAPT | |
| SCHEMBL30222 | 0.81 | HSD17B1 (0.79) | HSD17B1HSD17B2MAOBMAOAMAPT | |
| SCHEMBL31410 | 0.80 | HSD17B1 (0.73) | HSD17B1HSD17B2MAOBMAOAMAPT | |
| SCHEMBL8405382 | 0.78 | HSD17B1 (0.67) | HSD17B1HSD17B2MAOBMAOAMAPT | |
| SCHEMBL31384 | 0.77 | SCD (0.47) | HSD17B1HSD17B2MAPTSCDMEN1 | |
| SCHEMBL8404873 | 0.77 | HSD17B1 (0.72) | HSD17B1HSD17B2MAOBMAOAMAPT | |
| SCHEMBL4819801 | 0.77 | ALDH1A1 (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025638-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2012-03-01 | — | — | WO | disclosed |