SCHEMBL30666294

SCHEMBL30666294

NC(=O)c1cccc(C2CC2)c1N

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.39
MAPT P10636 2/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PARP1 P09874 10/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
ADRA1A P35348 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
AURKA O14965 1/20 0.38
RPS6KB1 P23443 1/20 0.38
METAP2 P50579 1/20 0.37
PARP2 Q9UGN5 1/20 0.37
GAA P10253 1/20 0.37
NOTUM Q6P988 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28853765 0.89 PARP1 (0.52) PARP1AURKARPS6KB1PARP2
SCHEMBL31748898 0.89 CYP11B1 (0.43) KDM4EALDH1A1PARP1SLC6A2SLC6A4
SCHEMBL161548 0.82 ADRA1A (0.51) KDM4EMAPTALDH1A1HPGDTSHR
SCHEMBL6383642 0.82 ADRA1A (0.51) KDM4EMAPTALDH1A1HPGDTSHR
SCHEMBL17786118 0.82 PARP1 (0.43) KDM4EALDH1A1TSHRPARP1MEN1
SCHEMBL9322018 0.82 PDK2 (0.38) ALDH1A1HPGDTSHRNOTUM
SCHEMBL29486223 0.82 SLC9A1 (0.45)
SCHEMBL4690983 0.81 KDM4E (0.49) KDM4EMAPTALDH1A1HPGDTSHR
SCHEMBL17786110 0.81 PARP1 (0.44) MAPTTSHRPARP1MEN1KMT2A
Hydrochloric Acid SCHEMBL30170745 0.81 ADRA1A (0.50) KDM4EMAPTALDH1A1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114423741-B aryl-N-aryl derivatives for the treatment of RNA viral infections ABIVAX公司 2023-11-07 CN disclosed