Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30666294 | 0.82 | KDM4E (0.39) | NOTUMALDH1A1TSHRHPGD | |
| SCHEMBL29486223 | 0.79 | SLC9A1 (0.45) | — | |
| SCHEMBL28280579 | 0.79 | KDM4E (0.39) | PDK2G6PDCASP7CASP6ALDH1A1 | |
| SCHEMBL7546990 | 0.77 | ALDH1A1 (0.42) | PDK2TAS1R3TAS1R1TAS1R2HSD11B1 | |
| SCHEMBL8141006 | 0.77 | MGLL (0.40) | PDK2G6PDCASP7CASP6HSD11B1 | |
| SCHEMBL30537929 | 0.77 | MGLL (0.40) | PDK2G6PDCASP7CASP6HSD11B1 | |
| SCHEMBL9274620 | 0.77 | HSD11B1 (0.41) | PDK2HSD11B1MGLLNPC1RAB9A | |
| SCHEMBL29486064 | 0.77 | ALDH1A1 (0.50) | PDK2CASP7NPSR1ALDH1A1TSHR | |
| SCHEMBL18029750 | 0.77 | SLC6A4 (0.42) | NOTUMTSHRHPGD | |
| SCHEMBL14625710 | 0.76 | G6PD (0.50) | NOTUMG6PDCASP7CASP6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5362911-A | Process for the preparation of o-aminophenyl cyclo-propyl ketone | AMERICAN CYANAMID COMPANY (US) | 1994-11-08 | — | — | US | disclosed |