Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.48 |
| ▸ | CTSS | P25774 | 4/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4542412 | 1.00 | CTSK (0.48) | CTSKCTSSPTGESRIPK1CTSB | |
| SCHEMBL4542411 | 1.00 | CTSK (0.48) | CTSKCTSSPTGESRIPK1CTSB | |
| SCHEMBL4839064 | 0.87 | CTSS (0.49) | CTSKCTSSRIPK1CTSBCTSL | |
| SCHEMBL4839068 | 0.87 | CTSS (0.49) | CTSKCTSSRIPK1CTSBCTSL | |
| SCHEMBL127326 | 0.85 | RIPK1 (0.60) | CTSKCTSSRIPK1CTSBCTSL | |
| SCHEMBL3349953 | 0.85 | RIPK1 (0.60) | CTSKCTSSRIPK1CTSBCTSL | |
| SCHEMBL2481921 | 0.85 | RIPK1 (0.60) | CTSKCTSSRIPK1CTSBCTSL | |
| SCHEMBL5020954 | 0.84 | CTSK (0.52) | CTSKCTSSRIPK1CTSBCTSL | |
| SCHEMBL5021539 | 0.84 | CTSK (0.52) | CTSKCTSSRIPK1CTSBCTSL | |
| SCHEMBL4537641 | 0.82 | RIPK1 (0.43) | PTGESRIPK1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49735-E1 | Oxazolidinones as modulators of MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-28 | — | — | US | disclosed |