Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 2/20 | 1.00 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.62 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | AHR | P35869 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3067442 | 0.78 | RXFP1 (1.00) | ALDH1A1HSD17B10HPGDALOX15RXFP1 | |
| SCHEMBL3057288 | 0.78 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HPGDALOX15RXFP1 | |
| SCHEMBL29650180 | 0.77 | TNKS2 (1.00) | ALDH1A1HSD17B10HPGDALOX15MAPT | |
| SCHEMBL377796 | 0.77 | TNKS2 (1.00) | ALDH1A1HSD17B10HPGDALOX15MAPT | |
| Hydrochloric Acid SCHEMBL30293259 | 0.75 | TNKS2 (0.96) | ALDH1A1HSD17B10HPGDALOX15MAPT | |
| SCHEMBL3071128 | 0.75 | ALDH1A1 (0.59) | ALDH1A1HSD17B10HPGDALOX15RXFP1 | |
| SCHEMBL3053313 | 0.73 | ALDH1A1 (0.59) | ALDH1A1HSD17B10HPGDALOX15RXFP1 | |
| Carbazole SCHEMBL27951197 | 0.70 | ALDH1A1 (0.74) | ALDH1A1HSD17B10HPGDALOX15MAPT | |
| SCHEMBL11613460 | 0.69 | KIF11 (0.66) | ALDH1A1HSD17B10HPGDALOX15MAPT | |
| SCHEMBL31474794 | 0.69 | KIF11 (0.66) | ALDH1A1HSD17B10HPGDALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399447-B2 | Metal triangulo compound and methods of using the same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2013-03-19 | — | — | US | disclosed |
| US-20100209431-A1 | METAL TRIANGULO COMPOUND AND METHODS OF USING THE SAME | NATIONAL UNIVERSITY OF SINGAPORE | 2010-08-19 | — | — | US | disclosed |
| EP-2147005-A1 | METAL TRIANGULO COMPOUND AND METHODS OF USING THE SAME | National University of Singapore (SG) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008127197-A1 | METAL TRIANGULO COMPOUND AND METHODS OF USING THE SAME | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2008-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100209431-A1 | METAL TRIANGULO COMPOUND AND METHODS OF USING THE SAME | CASP3, BAX, CASP7 | ALDH1A1 1447/4885HSD17B10 3305/4885HPGD 1967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.