Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30671841 | 0.88 | CYP19A1 (0.43) | CYP19A1CDC7MAPTOPRK1KMT2A | |
| SCHEMBL30671847 | 0.87 | CYP19A1 (0.43) | CYP19A1CDC7MAPTOPRK1KMT2A | |
| SCHEMBL17339063 | 0.78 | KMT2A (0.46) | MAPTKMT2AALDH1A1L3MBTL1RAB9A | |
| SCHEMBL27241000 | 0.78 | CDK2 (0.39) | CCNT1CCNE2CCNE1CDK2CDK9 | |
| SCHEMBL30671854 | 0.78 | CDK2 (0.39) | CCNT1CCNE2CCNE1CDK2CDK9 | |
| SCHEMBL30671853 | 0.78 | CDC7 (0.46) | CYP19A1CDC7MAPTKMT2AFGFR1 | |
| SCHEMBL19533519 | 0.72 | GLS (0.38) | CDC7CCNT1CCNE2CCNE1CDK2 | |
| SCHEMBL19533520 | 0.71 | FGFR1 (0.54) | MAPTOPRK1KMT2AFGFR1ALDH1A1 | |
| SCHEMBL2246276 | 0.70 | CYP19A1 (0.79) | CYP19A1MAPTKMT2AFGFR1ALDH1A1 | |
| SCHEMBL30584583 | 0.69 | ALDH1A1 (0.43) | CDK2MAPTPIN1OPRK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117136184-A | Aminopyrimidine compounds and methods of use thereof | 泰拉生物科学公司 | 2023-11-28 | — | — | CN | disclosed |