SCHEMBL30673333

SCHEMBL30673333

c1ccc2c(c1)-c1ccccc1C21CCCC1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PGR P06401 5/20 0.45
PDK2 Q15119 1/20 0.39
HTR2A P28223 1/20 0.38
THRB P10828 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
GPR84 Q9NQS5 1/20 0.38
S100A4 P26447 1/20 0.37
AKR1C1 Q04828 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
OPRK1 P41145 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29473421 1.00 PGR (0.45) PGRPDK2HTR2ATHRBTDP1
SCHEMBL4922107 1.00 PGR (0.45) PGRPDK2HTR2ATHRBTDP1
SCHEMBL29919493 0.97 PGR (0.46) PGRPDK2KDM4EESR1ESR2
SCHEMBL5894861 0.97 PGR (0.46) PGRPDK2KDM4EESR1ESR2
SCHEMBL29470989 0.95 THRB (0.43) PGRPDK2HTR2ATHRBTDP1
SCHEMBL29470987 0.95 THRB (0.43) PGRPDK2HTR2ATHRBTDP1
SCHEMBL4918697 0.89 GPR84 (0.43) PGRPDK2HTR2ATHRBTDP1
SCHEMBL28380514 0.86 THRB (0.38) PGRPDK2HTR2ATHRBTDP1
SCHEMBL6838754 0.83 ALDH1A1 (0.42) HTR2AESR1ESR2
SCHEMBL23959455 0.82 PDK2 (0.42) PGRPDK2TDP1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118475566-A Compound, material for organic electroluminescent element, and electronic device 出光兴产株式会社 2024-08-09 CN disclosed