Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.46 |
| ▸ | CA1 | P00915 | 13/20 | 0.46 |
| ▸ | CA6 | P23280 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 12/20 | 0.41 |
| ▸ | CA12 | O43570 | 9/20 | 0.41 |
| ▸ | CA5A | P35218 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17977218 | 0.81 | LDHA (0.47) | CA2CA1CA6CA4CA9 | |
| SCHEMBL30556213 | 0.79 | CA1 (0.38) | CA2CA1CA4CA9CA12 | |
| SCHEMBL29497318 | 0.76 | HTR7 (0.39) | CA1CA9CA12CYP2C9 | |
| SCHEMBL1863318 | 0.76 | HTR7 (0.39) | CA1CA9CA12CYP2C9 | |
| SCHEMBL9562554 | 0.74 | HTR7 (0.38) | CA1CA9CA12CYP2C9 | |
| SCHEMBL8958434 | 0.74 | TSHR (0.48) | CA2CA1CA4CA12CA5A | |
| SCHEMBL30490016 | 0.74 | TSHR (0.48) | CA2CA1CA4CA12CA5A | |
| SCHEMBL29878833 | 0.74 | ALDH1A1 (0.48) | CA1CA9CA12CYP2C9 | |
| SCHEMBL17595937 | 0.74 | CA2 (0.47) | CA2CA1CA6CA4CA9 | |
| SCHEMBL211750 | 0.74 | ALDH1A1 (0.48) | CA1CA9CA12CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143999-B | Cytotoxic and antimitotic compounds and methods of use thereof | 酵活英属哥伦比亚省公司 | 2023-12-05 | — | — | CN | disclosed |