SCHEMBL3067358

SCHEMBL3067358

NC(=O)c1cccc(=O)n1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 5/20 0.60
MMP1 P03956 1/20 0.44
MMP3 P08254 1/20 0.44
MMP7 P09237 1/20 0.44
MMP9 P14780 1/20 0.44
MMP8 P22894 1/20 0.44
MMP12 P39900 1/20 0.44
MMP13 P45452 1/20 0.44
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
HDAC9 Q9UKV0 1/20 0.39
HDAC5 Q9UQL6 1/20 0.39
KDM4E B2RXH2 2/20 0.37
LMNA P02545 1/20 0.35
MAP3K14 Q99558 1/20 0.35
PARP1 P09874 7/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2788070 0.80 IDH1 (0.62) IDH1MMP1MMP3MMP7MMP9
SCHEMBL13024178 0.80 IDH1 (0.62) IDH1MMP1MMP3MMP7MMP9
SCHEMBL22851936 0.78 IDH1 (0.60) IDH1MMP1MMP3MMP7MMP9
SCHEMBL2789862 0.78 IDH1 (0.60) IDH1MMP1MMP3MMP7MMP9
SCHEMBL28151832 0.78 IDH1 (0.41) IDH1KDM4ELMNAMAP3K14PARP1
SCHEMBL28151717 0.77 IDH1 (0.40) IDH1MMP1MMP3MMP7MMP9
SCHEMBL22724094 0.77 IDH1 (0.40) IDH1KDM4ELMNAMAP3K14PARP1
SCHEMBL23879792 0.74 IDH1 (0.55) IDH1MMP1MMP3MMP7MMP9
SCHEMBL21133302 0.74 IDH1 (0.55) IDH1MMP1MMP3MMP7MMP9
SCHEMBL22878855 0.74 IDH1 (0.55) IDH1MMP1MMP3MMP7MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109963839-A Chiral cycleanine compound and application thereof 香港理工大学 2019-07-02 CN claimed
EP-4727655-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF Mariana Oncology Inc. (US) 2026-04-22 EP disclosed
WO-2024259132-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC. (US) 2024-12-19 WO disclosed
US-20240304351-A1 SEPARATION OF METAL IONS BY LIQUID-LIQUID EXTRACTION UNIV CALIFORNIA (US) 2024-09-12 US disclosed
US-12002595-B2 Separation of metal ions by liquid-liquid extraction THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-04 US disclosed
EP-3986482-A1 IRON(III) AND GALLIUM(III) METAL ORGANIC POLYHEDRA, METHODS OF MAKING SAME, AND USES THEREOF The Research Foundation for The State University of New York (US) 2022-04-27 EP disclosed
US-20190287691-A1 SEPARATION OF METAL IONS BY LIQUID-LIQUID EXTRACTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-09-19 US disclosed
CN-109963839-A Chiral cycleanine compound and application thereof 香港理工大学 2019-07-02 CN disclosed
US-9556122-B2 Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-01-31 US disclosed
US-9556122-B2 Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-01-31 US disclosed
EP-2511266-A1 Luminescent 1-Hydroxy-2-Pyridinone Chelates of Lanthanides The Regents of The University of California (US) 2012-10-17 EP disclosed
US-8217173-B2 Fluoride-releasing compositions BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2012-07-10 US disclosed
US-20100261902-A1 Fluoride-Releasing Compositions BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (US) 2010-10-14 US disclosed
US-20100015725-A1 LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-01-21 US disclosed
US-20100015725-A1 LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-01-21 US disclosed
WO-2008008797-A2 LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-01-17 WO disclosed
WO-1994003169-A1 MIXTURE OF A FREE RADICAL SCAVENGER AND AN IRON CHELATOR FOR THE TREATMENT OF SICKLE CELL DISEASE BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-02-17 WO disclosed
EP-0397409-B1 THE STABILIZATION OF ORGANIC COMPOUNDS BTG INTERNATIONAL LIMITED (GB) 1993-07-21 EP disclosed
US-5185319-A STABILIZATION OF ORGANIC COMPOUNDS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1993-02-09 US disclosed
EP-0397409-A1 The stabilization of organic compounds BTG INTERNATIONAL LIMITED (GB) 1990-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190287691-A1 SEPARATION OF METAL IONS BY LIQUID-LIQUID EXTRACTION SLC39A14, SLC39A11, SLC39A7 IDH1 2049/4885MMP1 1517/4885MMP3 1745/4885
US-20100261902-A1 Fluoride-Releasing Compositions CHERP, ORAI1, CAD IDH1 3507/4885MMP1 749/4885MMP3 1941/4885
US-12002595-B2 Separation of metal ions by liquid-liquid extraction SLC39A14, SLC39A11, SLC39A7 IDH1 2049/4885MMP1 1517/4885MMP3 1745/4885
US-20100015725-A1 LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES PLPBP, HPD, LASP1 IDH1 25/4885MMP1 945/4885MMP3 1614/4885
US-20240304351-A1 SEPARATION OF METAL IONS BY LIQUID-LIQUID EXTRACTION SLC39A14, SLC39A11, SLC39A7 IDH1 2049/4885MMP1 1517/4885MMP3 1745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.