Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.46 |
| ▸ | MMP14 | P50281 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29121987 | 1.00 | NR4A2 (0.46) | NR4A2MMP14KDM4EALDH1A1TDP1 | |
| SCHEMBL29503951 | 0.79 | KDM4E (0.50) | NR4A2MMP14KDM4EALDH1A1TDP1 | |
| SCHEMBL440421 | 0.79 | KDM4E (0.50) | NR4A2MMP14KDM4EALDH1A1TDP1 | |
| SCHEMBL30676376 | 0.77 | KDM4E (0.46) | NR4A2MMP14KDM4EALDH1A1TDP1 | |
| SCHEMBL18984790 | 0.77 | KDM4E (0.46) | NR4A2MMP14KDM4EALDH1A1TDP1 | |
| SCHEMBL15255189 | 0.77 | KDM4E (0.48) | NR4A2MMP14KDM4EALDH1A1TDP1 | |
| SCHEMBL2515670 | 0.75 | NR4A2 (0.61) | NR4A2MMP14KDM4EALDH1A1TDP1 | |
| SCHEMBL31452767 | 0.74 | MMP14 (0.53) | NR4A2MMP14KDM4EALDH1A1TDP1 | |
| SCHEMBL10686979 | 0.72 | CYP1A2 (0.54) | NR4A2MMP14KDM4EALDH1A1TDP1 | |
| SCHEMBL6537974 | 0.72 | LMNA (0.50) | NR4A2MMP14KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120419-A | KLK5 bicyclic heteroaromatic inhibitors | 拜奥克里斯特制药公司 | 2023-11-24 | — | — | CN | disclosed |