Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.61 |
| ▸ | MMP14 | P50281 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | METAP2 | P50579 | 2/20 | 0.47 |
| ▸ | METAP1 | P53582 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434767 | 0.84 | HSP90AA1 (0.61) | NR4A2MMP14ALDH1A1MEN1KMT2A | |
| SCHEMBL2423195 | 0.84 | HSP90AA1 (0.61) | NR4A2MMP14ALDH1A1MEN1KMT2A | |
| SCHEMBL29410781 | 0.81 | NR4A2 (0.68) | NR4A2MMP14ALDH1A1MEN1KMT2A | |
| SCHEMBL30668493 | 0.81 | NR4A2 (0.68) | NR4A2MMP14ALDH1A1MEN1KMT2A | |
| SCHEMBL318769 | 0.81 | NR4A2 (0.68) | NR4A2MMP14ALDH1A1MEN1KMT2A | |
| SCHEMBL6629560 | 0.81 | NR4A2 (0.68) | NR4A2MMP14ALDH1A1MEN1KMT2A | |
| SCHEMBL18434587 | 0.77 | KDM4E (0.46) | NR4A2MMP14ALDH1A1MEN1KMT2A | |
| SCHEMBL3630037 | 0.76 | KDM4E (0.53) | NR4A2MMP14ALDH1A1MEN1KMT2A | |
| SCHEMBL10009591 | 0.76 | NR4A2 (1.00) | NR4A2MMP14ALDH1A1MEN1KMT2A | |
| SCHEMBL317120 | 0.76 | HTR1A (0.56) | NR4A2MMP14ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025091127-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | UNIVERSITE DE MONTREAL (CA) | 2025-05-08 | — | — | WO | disclosed |
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-07-18 | — | — | US | disclosed |
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-07-18 | — | — | US | disclosed |
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-07-18 | — | — | US | disclosed |
| CN-117120419-A | KLK5 bicyclic heteroaromatic inhibitors | 拜奥克里斯特制药公司 | 2023-11-24 | — | — | CN | disclosed |
| US-11731970-B1 | Pyrrolo[2,3-b]quinoline compounds as antibacterial agents | King Faisal University (SA) | 2023-08-22 | — | — | US | disclosed |
| US-20220081412-A1 | QUINOLINYL-PYRAZINE-CARBOXAMIDE COMPOUNDS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2022-03-17 | — | — | US | disclosed |
| WO-2020132459-A1 | QUINOLINYL-PYRAZINE-CARBOXAMIDE COMPOUNDS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-06-25 | — | — | WO | disclosed |
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |
| CN-105237476-A | Synthetic method for 4-chloro-8-aminoquinoline | GAO DAYUAN | 2016-01-13 | — | — | CN | disclosed |
| CN-1551877-A | Piperidine derivatives useful as CCR5 antagonists | ���鹫˾ | 2004-12-01 | — | — | CN | disclosed |
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |
| EP-1421075-A1 | PIPERIDINE DERIVATIVES USEFUL AS CCR5 ANTAGONISTS | Schering Corporation (US) | 2004-05-26 | — | — | EP | disclosed |
| US-20040092745-A1 | Piperidine derivatives useful as CCR5 antagonists | PALANI ANANDAN (US) | 2004-05-13 | — | — | US | disclosed |
| US-20040092551-A1 | Piperidine derivatives useful as CCR5 antagonists | PALANI ANANDAN (US) | 2004-05-13 | — | — | US | disclosed |
| US-20040010008-A1 | Piperidine derivatives useful as CCR5 antagonists | SCHERING CORPORATION | 2004-01-15 | — | — | US | disclosed |
| WO-2003020716-A1 | PIPERIDINE DERIVATIVES USEFUL AS CCR5 ANTAGONISTS | SCHERING CORPORATION (US) | 2003-03-13 | — | — | WO | disclosed |
| US-6008230-A | TREATING BONE DISEASES CAUSED BY ABNORMAL BONE METABOLISM IN HUMAN BEING OR ANIMALS AS THE INHIBITORS OF BONE RESORPTION OR THE INHIBITORS OF BONE METASTASIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0876345-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997014681-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092551-A1 | Piperidine derivatives useful as CCR5 antagonists | CCR5, CCR1, CXCR3 | NR4A2 1472/4885MMP14 2410/4885ALDH1A1 864/4885 |
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | KLK5, KLK1, KLKB1 | NR4A2 2887/4885MMP14 435/4885ALDH1A1 1532/4885 |
| US-20220081412-A1 | QUINOLINYL-PYRAZINE-CARBOXAMIDE COMPOUNDS AND USES THEREOF | HMGB3, HCCS, ACACA | NR4A2 1000/4885MMP14 4540/4885ALDH1A1 2869/4885 |
| US-11731970-B1 | Pyrrolo[2,3-b]quinoline compounds as antibacterial agents | POLB, TOP2A, POLR2B | NR4A2 1312/4885MMP14 1534/4885ALDH1A1 3817/4885 |
| US-20040010008-A1 | Piperidine derivatives useful as CCR5 antagonists | CCR5, CCR1, CXCR3 | NR4A2 1472/4885MMP14 2410/4885ALDH1A1 864/4885 |
| US-20040092745-A1 | Piperidine derivatives useful as CCR5 antagonists | CCR5, CCR1, CXCR3 | NR4A2 1472/4885MMP14 2410/4885ALDH1A1 864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.