Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.48 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.48 |
| ▸ | PPID | Q08752 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23252438 | 0.83 | KMT2A (0.55) | MEN1KMT2AMLLT1HRH3KDM4E | |
| SCHEMBL3126965 | 0.83 | NPC1 (0.57) | MEN1KMT2AMLLT1HRH3KDM4E | |
| SCHEMBL4197501 | 0.83 | KDM4E (0.69) | MEN1KMT2AHRH3KDM4ETPSAB1 | |
| SCHEMBL30677754 | 0.82 | KMT2A (0.60) | MEN1KMT2AHRH3ALDH1A1 | |
| SCHEMBL6559744 | 0.81 | KDM4E (0.68) | MEN1KMT2AHRH3KDM4ETPSAB1 | |
| SCHEMBL5217325 | 0.81 | KDM4E (0.68) | MEN1KMT2AHRH3KDM4ETPSAB1 | |
| SCHEMBL4559263 | 0.80 | TP53 (0.63) | MEN1KMT2ATPSAB1TPSD1TPSG1 | |
| SCHEMBL5800630 | 0.79 | KDM4E (0.69) | MEN1KMT2AHRH3KDM4ETPSAB1 | |
| SCHEMBL5146467 | 0.79 | TPSAB1 (0.50) | MEN1KMT2AMLLT1HRH3KDM4E | |
| SCHEMBL5740992 | 0.78 | HRH3 (0.59) | MEN1KMT2AMLLT1HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007107539-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-09-27 | — | — | WO | disclosed |