Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LIPA | P38571 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31111632 | 0.75 | ALDH1A1 (0.51) | ALDH1A1POLBMEN1KMT2AHSD17B10 | |
| SCHEMBL2050164 | 0.75 | ALDH1A1 (0.51) | ALDH1A1POLBMEN1KMT2AHSD17B10 | |
| SCHEMBL30515023 | 0.71 | ALDH1A1 (0.50) | ALDH1A1POLBMEN1KMT2AHSD17B10 | |
| SCHEMBL30473912 | 0.69 | ALDH1A1 (0.56) | ALDH1A1POLBMEN1KMT2AHSD17B10 | |
| SCHEMBL28673249 | 0.69 | KMT2A (0.62) | ALDH1A1POLBMEN1KMT2AHSD17B10 | |
| SCHEMBL28558035 | 0.69 | SMN1; SMN2 (0.49) | ALDH1A1POLBMEN1KMT2ALIPA | |
| SCHEMBL22978700 | 0.66 | ALDH1A1 (0.47) | ALDH1A1POLBMEN1KMT2AHSD17B10 | |
| SCHEMBL31629008 | 0.66 | ALDH1A1 (0.51) | ALDH1A1POLBMEN1KMT2AHSD17B10 | |
| SCHEMBL31127701 | 0.66 | ALDH1A1 (0.51) | ALDH1A1POLBMEN1KMT2AHSD17B10 | |
| SCHEMBL31589528 | 0.65 | ALDH1A1 (0.50) | ALDH1A1POLBMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157298-A | Dual-function chimeric heterocyclic compound of interleukin-1 receptor related kinase 4, preparation method, medicinal composition and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2023-12-01 | — | — | CN | disclosed |