Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924416 | 0.86 | MEN1 (0.33) | MEN1KMT2AUSP7 | |
| SCHEMBL30259333 | 0.86 | MKNK2 (0.35) | PTGER4MEN1KMT2AMAPK1MRGPRX4 | |
| SCHEMBL29555150 | 0.77 | BRD4 (0.43) | MAPK1USP2LMNAUSP7MTNR1A | |
| SCHEMBL29924291 | 0.77 | PTGER4 (0.35) | PTGER4 | |
| SCHEMBL30538743 | 0.76 | KMT2A (0.42) | PTGER4MEN1KMT2AHPGDMAPK1 | |
| SCHEMBL29079760 | 0.75 | ALDH1A1 (0.40) | PTGER4MEN1KMT2AHPGDMAPK1 | |
| SCHEMBL29558931 | 0.75 | ALDH1A1 (0.40) | PTGER4MEN1KMT2AHPGDMAPK1 | |
| SCHEMBL29079758 | 0.75 | ALDH1A1 (0.40) | PTGER4MEN1KMT2AHPGDMAPK1 | |
| SCHEMBL24174887 | 0.72 | MAPK1 (0.42) | PTGER4MEN1KMT2AMAPK1 | |
| SCHEMBL30538800 | 0.71 | MEN1 (0.32) | MEN1KMT2AUSP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |