Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14625577 | 0.81 | PTGDR (0.37) | POLBSLC6A4SLC6A3SRD5A1HDAC6 | |
| SCHEMBL29924296 | 0.77 | PTGDR (0.47) | SLC6A4SLC6A3 | |
| SCHEMBL24685578 | 0.74 | HTR2C (0.41) | SLC6A4SRD5A1 | |
| SCHEMBL30680720 | 0.72 | BACE1 (0.35) | SLC6A4SLC6A3SRD5A1BACE1MAP3K14 | |
| SCHEMBL30680744 | 0.71 | SLC6A4 (0.33) | SLC6A4SLC6A3SRD5A1HDAC6BACE1 | |
| SCHEMBL29924946 | 0.69 | ICMT (0.38) | POLBSLC6A4SLC6A3SRD5A1HDAC6 | |
| SCHEMBL29947353 | 0.69 | KMT2A (0.31) | BACE1 | |
| SCHEMBL30404309 | 0.69 | KMT2A (0.31) | BACE1 | |
| SCHEMBL29924550 | 0.69 | KMT2A (0.31) | BACE1 | |
| SCHEMBL24186494 | 0.68 | BACE1 (0.39) | HDAC6BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |