Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14625577 | 0.91 | PTGDR (0.37) | PTGDRPTGDR2SLC6A4SLC6A3 | |
| SCHEMBL24685578 | 0.83 | HTR2C (0.41) | PTGDRPTGDR2SLC6A4SLC6A2 | |
| SCHEMBL30680720 | 0.80 | BACE1 (0.35) | PTGDRPTGDR2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL20628768 | 0.79 | BACE1 (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21291315 | 0.79 | SLC6A3 (0.54) | PTGDRPTGDR2SLC6A4SLC6A3PDE7A | |
| SCHEMBL17192882 | 0.78 | PTGDR (0.46) | PTGDRPTGDR2SLC6A4SLC6A3PDE7A | |
| SCHEMBL30680705 | 0.77 | POLB (0.32) | SLC6A4SLC6A3 | |
| SCHEMBL22400205 | 0.76 | BACE1 (0.46) | — | |
| SCHEMBL29924946 | 0.74 | ICMT (0.38) | SLC6A4SLC6A3PGR | |
| SCHEMBL17186925 | 0.73 | PRKAB2 (0.44) | SLC6A4SLC6A3PDE7APSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |