Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CFTR | P13569 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3460031 | 0.77 | SPR (0.47) | ALDH1A1KDM4EADORA3TP53POLB | |
| SCHEMBL3459056 | 0.77 | APOBEC3A (0.49) | ALDH1A1KDM4ETDP1MAPTNPC1 | |
| SCHEMBL30680974 | 0.75 | ADORA3 (0.44) | ALDH1A1KDM4ESMN1; SMN2ADORA3TP53 | |
| SCHEMBL30680957 | 0.70 | BRD9 (0.45) | ADORA3TP53POLBTDP1NPC1 | |
| Trifluoroacetic Acid SCHEMBL5441300 | 0.70 | KDR (0.35) | — | |
| SCHEMBL4869136 | 0.67 | TP53 (0.67) | KDM4ESMN1; SMN2TP53POLBTDP1 | |
| SCHEMBL3461693 | 0.67 | TP53 (0.43) | ALDH1A1KDM4ESMN1; SMN2CFTRTP53 | |
| SCHEMBL3461691 | 0.66 | HPGD (0.44) | ALDH1A1KDM4ESMN1; SMN2CFTRTP53 | |
| SCHEMBL22148137 | 0.65 | CA12 (0.46) | KDM4ESMN1; SMN2TP53POLBMAPT | |
| Trifluoroacetic Acid SCHEMBL27604316 | 0.65 | MAPT (0.56) | ALDH1A1KDM4ESMN1; SMN2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244672-A1 | 2-(IMIDAZO[1, 2-A]1,8-NAPHTHYRIDIN-8-YL)-1,3,4-OXADIAZOLE DERIVATIVES AS ENHANCERS OF INNATE IMMUNE RESPONSE FOR THE TREATMENT OF VIRAL INFECTIONS | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-12-21 | — | — | WO | disclosed |