Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28573813 | 0.85 | SPR (0.47) | ADORA3TP53POLBMAPTCYP1A2 | |
| SCHEMBL29079139 | 0.81 | APOBEC3A (0.49) | TDP1MAPTKDM4EALDH1A1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL30680968 | 0.75 | ALDH1A1 (0.41) | ADORA3TP53POLBTDP1MAPT | |
| SCHEMBL13517074 | 0.75 | MAP4K4 (0.60) | MAPTHSD17B10 | |
| SCHEMBL30680957 | 0.74 | BRD9 (0.45) | ADORA3TP53POLBTDP1LMNA | |
| SCHEMBL4869136 | 0.74 | TP53 (0.67) | TP53POLBTDP1MAPTKDM4E | |
| SCHEMBL31210663 | 0.73 | AHR (0.35) | MAPT | |
| SCHEMBL31211167 | 0.71 | AHR (0.38) | — | |
| SCHEMBL27160727 | 0.71 | KDM4E (0.41) | MAPTCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL25347174 | 0.71 | ADORA3 (0.39) | ADORA3TP53POLBTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244672-A1 | 2-(IMIDAZO[1, 2-A]1,8-NAPHTHYRIDIN-8-YL)-1,3,4-OXADIAZOLE DERIVATIVES AS ENHANCERS OF INNATE IMMUNE RESPONSE FOR THE TREATMENT OF VIRAL INFECTIONS | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-12-21 | — | — | WO | disclosed |