Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 11/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29437720 | 0.88 | AR (0.55) | ADORA1ADORA2AARKDM4EALDH1A1 | |
| SCHEMBL11590712 | 0.88 | AR (0.55) | ADORA1ADORA2AARKDM4EALDH1A1 | |
| SCHEMBL11716661 | 0.78 | ALDH1A1 (0.35) | ARALDH1A1KMT2APDE2A | |
| SCHEMBL11723632 | 0.77 | KDM4E (0.40) | ADORA1ADORA2AKDM4EALDH1A1KMT2A | |
| SCHEMBL30680914 | 0.77 | ADORA1 (0.57) | ADORA1ADORA2ACA5AKDM4EALDH1A1 | |
| SCHEMBL11591796 | 0.76 | ADORA1 (0.53) | ADORA1ADORA2ACA5AKDM4EALDH1A1 | |
| SCHEMBL7978388 | 0.73 | ADORA1 (0.61) | ADORA1ADORA2ACA5AKDM4EALDH1A1 | |
| SCHEMBL11592378 | 0.70 | ADORA1 (0.53) | ADORA1ADORA2AARCA5AKDM4E | |
| SCHEMBL31624491 | 0.70 | ADORA1 (0.60) | ADORA1ADORA2ACA5AKDM4EALDH1A1 | |
| SCHEMBL11716981 | 0.68 | ALDH1A1 (0.67) | KDM4EALDH1A1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025128898-A1 | IMIDAZO[1,2-A][1,8]NAPHTHYRIDINE DERIVATIVES AS ENHANCERS OF INNATE IMMUNE RESPONSE FOR THE TREATMENT OF VIRAL INFECTIONS | ASSEMBLY BIOSCIENCES, INC. (US) | 2025-06-19 | — | — | WO | disclosed |
| WO-2023244672-A1 | 2-(IMIDAZO[1, 2-A]1,8-NAPHTHYRIDIN-8-YL)-1,3,4-OXADIAZOLE DERIVATIVES AS ENHANCERS OF INNATE IMMUNE RESPONSE FOR THE TREATMENT OF VIRAL INFECTIONS | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-12-21 | — | — | WO | disclosed |