SCHEMBL3068273

SCHEMBL3068273

Clc1ccccc1C1(C2(c3ccccc3Cl)N=CC(c3ccccc3)(c3ccccc3)N2)N=CC(c2ccccc2)(c2ccccc2)N1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8204687 0.60 LMNA (0.41) CRHBPCRHR2
SCHEMBL11594199 0.58 CRHBP (0.37) CRHBPCRHR2
SCHEMBL8497537 0.56 GRIN1 (0.42) CRHBPCRHR2
1,2-Dichlorobenzene SCHEMBL11850148 0.55 TSHR (0.91)
SCHEMBL31506444 0.55 LMNA (0.45) CRHBPCRHR2
SCHEMBL21881119 0.54 PDK2 (0.50) CRHBPCRHR2
SCHEMBL8205124 0.54 GRIN1 (0.37) CRHBPCRHR2
SCHEMBL11703341 0.53 ALDH1A1 (0.33)
SCHEMBL11453271 0.53 CFTR (0.37)
SCHEMBL11993802 0.53 HDAC4 (0.44) CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100221663-A1 LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL, AND IMAGE FORMATION METHOD EMPLOYING THE SAME KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2010-09-02 US disclosed