Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26931975 | 0.88 | RAB9A (0.35) | AAK1 | |
| SCHEMBL30683031 | 0.87 | AAK1 (0.41) | AAK1RORCNAMPTKDM4AL3MBTL1 | |
| SCHEMBL26932140 | 0.85 | PRMT5 (0.34) | NAMPTPRMT5WDR77KDM4AL3MBTL1 | |
| SCHEMBL30683019 | 0.85 | PRMT5 (0.34) | NAMPTPRMT5WDR77KDM4AL3MBTL1 | |
| SCHEMBL30683098 | 0.83 | GABRA1 (0.36) | NAMPTPRMT5WDR77KDM4AL3MBTL1 | |
| SCHEMBL26932126 | 0.83 | GABRA1 (0.36) | NAMPTPRMT5WDR77KDM4AL3MBTL1 | |
| SCHEMBL20669674 | 0.82 | AAK1 (0.44) | AAK1KDM4AL3MBTL1MAPKAPK2 | |
| SCHEMBL30683062 | 0.77 | DUT (0.30) | — | |
| SCHEMBL16814130 | 0.77 | AAK1 (0.51) | AAK1RORCNAMPTPRMT5WDR77 | |
| SCHEMBL29918736 | 0.77 | AAK1 (0.51) | AAK1RORCNAMPTPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |