Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.44 |
| ▸ | MPO | P05164 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BUB1 | O43683 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27035550 | 1.00 | KIF11 (0.44) | KIF11MPOAKR1C3AKR1C2RXFP1 | |
| SCHEMBL30683308 | 0.89 | JAK2 (0.39) | KIF11AKR1C3AKR1C2 | |
| SCHEMBL27035626 | 0.89 | JAK2 (0.39) | KIF11AKR1C3AKR1C2 | |
| SCHEMBL27035576 | 0.80 | TEAD1 (0.52) | KIF11AKR1C3AKR1C2PTK6BUB1 | |
| SCHEMBL27067091 | 0.72 | AKR1C3 (0.42) | KIF11AKR1C3AKR1C2LMNAALDH1A1 | |
| SCHEMBL31374699 | 0.71 | AKR1C3 (0.41) | KIF11AKR1C3AKR1C2RXFP1 | |
| SCHEMBL27035554 | 0.71 | JAK2 (0.38) | KIF11AKR1C3AKR1C2 | |
| SCHEMBL27035563 | 0.71 | AKR1C3 (0.41) | KIF11AKR1C3AKR1C2RXFP1 | |
| SCHEMBL30683313 | 0.71 | TEAD1 (0.37) | KIF11AKR1C3AKR1C2 | |
| SCHEMBL27035687 | 0.71 | TEAD1 (0.37) | KIF11AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558485-A1 | TEAD INHIBITORS AND METHODS OF USE | Sporos Biodiscovery, Inc. (US) | 2025-05-28 | — | — | EP | disclosed |
| CN-119497708-A | TEAD inhibitors and methods of use | 思博睿生物探索公司 | 2025-02-21 | — | — | CN | disclosed |
| WO-2024020350-A1 | TEAD INHIBITORS AND METHODS OF USE | SPOROS BIODISCOVERY, INC. (US) | 2024-01-25 | — | — | WO | disclosed |