Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20743706 | 1.00 | TDO2 (0.39) | TDO2TLR8TLR7TLR9MAP4K4 | |
| SCHEMBL23012692 | 0.87 | ADORA2B (0.43) | MAP4K4HRH4AAK1DYRK1ANFATC1 | |
| SCHEMBL20744447 | 0.87 | DYRK1A (0.39) | TLR8TLR7TLR9HRH4AAK1 | |
| SCHEMBL29573583 | 0.87 | ADORA2B (0.43) | MAP4K4HRH4AAK1DYRK1ANFATC1 | |
| SCHEMBL22374010 | 0.85 | CCNC (0.39) | TDO2CCNCCDK8AAK1PSEN1 | |
| SCHEMBL20744379 | 0.84 | ALOX5AP (0.36) | HRH4 | |
| SCHEMBL20754870 | 0.82 | HRH4 (0.40) | TLR8TLR7TLR9HRH4DYRK1A | |
| SCHEMBL20744369 | 0.82 | MAP4K4 (0.41) | TDO2MAP4K4HRH4AAK1PSEN1 | |
| SCHEMBL20754538 | 0.82 | MAP4K4 (0.41) | TLR8TLR7TLR9MAP4K4HRH4 | |
| SCHEMBL20609796 | 0.82 | NLRP3 (0.48) | AAK1MTORDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132974-B | Sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2023-11-21 | — | — | CN | disclosed |