SCHEMBL20744447

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29573583	0.88	ADORA2B (0.43)	DYRK1AALOX5APFEN1HRH4AAK1
	SCHEMBL23012692	0.88	ADORA2B (0.43)	DYRK1AALOX5APFEN1HRH4AAK1
	SCHEMBL20743706	0.87	TDO2 (0.39)	DYRK1AHRH4AAK1TLR9TLR8
	SCHEMBL30684113	0.87	TDO2 (0.39)	DYRK1AHRH4AAK1TLR9TLR8
	SCHEMBL20744379	0.86	ALOX5AP (0.36)	ALOX5APFEN1HRH4MAPK14NLRP3
	SCHEMBL21725517	0.84	ABL1 (0.42)	DYRK1AALOX5APFEN1HRH4AAK1
	SCHEMBL20744369	0.83	MAP4K4 (0.41)	ALOX5APFEN1HRH4AAK1MAPK14
	SCHEMBL20609796	0.83	NLRP3 (0.48)	DYRK1AAAK1MAPK14MAPK13MAPK12
	SCHEMBL20754538	0.83	MAP4K4 (0.41)	ALOX5APFEN1HRH4AAK1TLR9
	SCHEMBL20754870	0.83	HRH4 (0.40)	DYRK1AALOX5APFEN1HRH4TLR9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.