SCHEMBL30686563

SCHEMBL30686563

NC(=O)C1(c2nc(Cl)ccc2Br)CC1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
FLT4 P35916 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30686633 0.94 HDAC4 (0.36) ALDH1A1FLT4
SCHEMBL31368977 0.90 ALOX5 (0.36) ALDH1A1POLB
SCHEMBL31368891 0.84 ALOX5 (0.33)
SCHEMBL23649733 0.81 ALDH1A1 (0.33) ALDH1A1GAA
SCHEMBL30041394 0.81 ALDH1A1 (0.33) ALDH1A1GAA
SCHEMBL22615348 0.73 SMN1; SMN2 (0.36) ALDH1A1
SCHEMBL14920534 0.71 PLAU (0.44) ALDH1A1FLT4
SCHEMBL29974597 0.70 FLT4 (0.34) ALDH1A1FLT4
SCHEMBL25361093 0.69 IKBKB (0.37) ALDH1A1FLT4POLBGAA
SCHEMBL30495081 0.69 IKBKB (0.37) ALDH1A1FLT4POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532496-A1 NOVEL PAR-2 INHIBITORS Domain Therapeutics (FR) 2025-04-09 EP disclosed
CN-119384420-A Novel PAR-2 inhibitors 多曼治疗学公司 2025-01-28 CN disclosed
WO-2023233033-A1 NOVEL PAR-2 INHIBITORS DOMAIN THERAPEUTICS (FR) 2023-12-07 WO disclosed