Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25090898 | 0.84 | PLAU (0.41) | PLAUOPRL1OPRM1NPC1RAB9A | |
| SCHEMBL14920146 | 0.78 | ALDH1A1 (0.50) | PLAUKMT2AHTTRAB9AMEN1 | |
| SCHEMBL20599442 | 0.73 | PLAU (0.32) | PLAUOPRL1OPRM1KMT2AHTT | |
| SCHEMBL12002669 | 0.73 | OPRM1 (0.33) | PLAUOPRL1OPRM1KDM4EALDH1A1 | |
| SCHEMBL23580162 | 0.72 | PLAU (0.40) | PLAUKMT2AHTTSMN1; SMN2 | |
| SCHEMBL38660622 | 0.72 | OPRL1 (0.38) | PLAUOPRL1OPRM1FLT4 | |
| SCHEMBL20525131 | 0.72 | OPRL1 (0.38) | PLAUOPRL1OPRM1FLT4 | |
| SCHEMBL27020188 | 0.71 | PLAU (0.39) | PLAUKMT2AHTTNPC1RAB9A | |
| SCHEMBL30686563 | 0.71 | ALDH1A1 (0.32) | FLT4ALDH1A1 | |
| SCHEMBL14919971 | 0.71 | PLAU (0.39) | PLAUKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773617-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-22 | — | — | EP | disclosed |
| US-20150223456-A1 | PESTICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2015-08-13 | — | — | US | disclosed |
| US-9040708-B2 | Pesticidal compounds | SYNGENTA LIMITED (GB) | 2015-05-26 | — | — | US | disclosed |
| US-20140296067-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | US | disclosed |
| EP-2773617-A1 | PESTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064521-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150223456-A1 | PESTICIDAL COMPOUNDS | C5, CBR3, C3AR1 | PLAU 4123/4885OPRL1 1569/4885OPRM1 1421/4885 |
| US-20140296067-A1 | PESTICIDAL COMPOUNDS | C5, CBR3, C3AR1 | PLAU 4123/4885OPRL1 1569/4885OPRM1 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.