SCHEMBL30687464

SCHEMBL30687464

O=S(=O)(Cl)c1cc(Br)n2nccc2c1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25249404 0.71 TTR (0.37) ALDH1A1
SCHEMBL25120213 0.70 ALDH1A1 (0.31) ALDH1A1HSD17B10TDP1
SCHEMBL25239224 0.70 PARP1 (0.37) HSD17B10TDP1
SCHEMBL30713186 0.69 DGAT1 (0.33)
SCHEMBL15739665 0.69 ALDH1A1 (0.42) ALDH1A1HSD17B10TDP1
SCHEMBL25237230 0.67 KDM4E (0.40) ALDH1A1HSD17B10TDP1
SCHEMBL2715907 0.66 DRD2 (0.36)
SCHEMBL30521100 0.66 ALDH1A1 (0.30) ALDH1A1
SCHEMBL24387027 0.62 PDE10A (0.44)
SCHEMBL26631423 0.61 DGAT1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4549438-A1 FIVE-MEMBERED AND SIX-MEMBERED NITROGEN-CONTAINING COMPOUND, AND INTERMEDIATE, PREPARATION METHOD AND USE THEREOF Hangzhou Synrx Therapeutics Biomedical Technology Co., Ltd. (CN) 2025-05-07 EP disclosed
WO-2024002284-A1 FIVE-MEMBERED AND SIX-MEMBERED NITROGEN-CONTAINING COMPOUND, AND INTERMEDIATE, PREPARATION METHOD AND USE THEREOF 杭州圣域生物医药科技有限公司 2024-01-04 WO disclosed
CN-117304183-A Five-membered and six-membered nitrogen-containing compound, intermediate thereof, preparation method and application 杭州圣域生物医药科技有限公司 2023-12-29 CN disclosed