Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26682643 | 0.89 | OPRD1 (0.44) | ITGB3ITGA2BMAPTLMNAHSD17B10 | |
| SCHEMBL30687773 | 0.88 | RXRA (0.49) | RXRARXRBITGB3ITGA2BDRD2 | |
| SCHEMBL26680482 | 0.88 | RXRA (0.49) | RXRARXRBITGB3ITGA2BDRD2 | |
| SCHEMBL26680378 | 0.87 | CCR5 (0.48) | RXRARXRBCCR5ITGB3ITGA2B | |
| SCHEMBL26681019 | 0.87 | TP53 (0.44) | DRD2DRD3MAPTLMNAHSD17B10 | |
| SCHEMBL30687630 | 0.87 | TP53 (0.44) | DRD2DRD3MAPTLMNAHSD17B10 | |
| SCHEMBL26682632 | 0.87 | BCL2 (0.47) | MAPTLMNAHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL26681667 | 0.87 | KMT2A (0.42) | CCR5ITGB3ITGA2BDRD2DRD3 | |
| SCHEMBL26681374 | 0.86 | MAPT (0.63) | MAPTLMNAHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL26682956 | 0.85 | ITGB3 (0.44) | ITGB3ITGA2BDRD2DRD3ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279476-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-22 | — | — | EP | disclosed |