SCHEMBL30688239

SCHEMBL30688239

CCCCCC(C)(C)C.O=C(O)NCCNC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 8/20 0.42
CASP2 P42575 1/20 0.38
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CES2 O00748 1/20 0.37
PLA2G2A P14555 1/20 0.37
AKR1B1 P15121 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL9635222 0.83 AKR1B1 (0.46) MEN1KMT2ACES2AKR1B1
Bicarbonate SCHEMBL28388669 0.81 CES2 (0.48) MEN1KMT2ACES2
SCHEMBL21244984 0.80 CA3 (0.42) MEN1KMT2A
SCHEMBL11127322 0.79 ALDH1A1 (0.44) MEN1KMT2ACES2AKR1B1
SCHEMBL176011 0.78
Hexane SCHEMBL28335720 0.78 EPHX1 (0.62) EPHX1CASP2PLA2G2A
SCHEMBL5489345 0.78 SIGMAR1 (0.44)
Hydrogen Peroxide SCHEMBL28990433 0.78 TSHR (0.47) CES2
Chloromethane SCHEMBL28123599 0.77 EPHX1 (0.58) EPHX1CASP2MEN1KMT2AL3MBTL1
SCHEMBL2440729 0.76 EPHX1 (0.70) EPHX1CASP2L3MBTL1PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3880155-B1 BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS DENTSPLY DETREY GMBH (DE) 2023-12-27 EP disclosed