Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28698395 | 0.84 | SMN1; SMN2 (0.38) | TSHRRECQLHPGDSMN1; SMN2POLB | |
| SCHEMBL31484611 | 0.81 | RECQL (0.39) | TSHRRECQLSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL28911826 | 0.79 | USP2 (0.36) | CA2RECQLCA12CA1CA9 | |
| SCHEMBL19948679 | 0.76 | SIGMAR1 (0.40) | TSHRHPGDSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL25263099 | 0.75 | CA2 (0.41) | TSHRCA2RECQLCA12CA1 | |
| SCHEMBL30781577 | 0.74 | PRMT5 (0.39) | CA2CA12CA1CA9ALDH1A1 | |
| SCHEMBL3292028 | 0.74 | CA2 (0.39) | TSHRCA2RECQLCA12CA1 | |
| SCHEMBL30477380 | 0.73 | ERN1 (0.31) | SIGMAR1 | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL113765 | 0.73 | TSHR (0.57) | TSHRCA2RECQLCA12CA1 | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL3889276 | 0.73 | TSHR (0.57) | TSHRCA2RECQLCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775260-A | Pyrimidine-2, 4 (1H, 3H) -dione compounds, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2025-04-08 | — | — | CN | disclosed |
| CN-115703792-B | Tricycle derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-114907387-B | Pyrimido pyrrole KRAS inhibitor and preparation method and application thereof | 中山大学 | 2023-11-10 | — | — | CN | disclosed |