Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22403860 | 1.00 | TAS2R14 (0.52) | TAS2R14NOTUMLMNAGAATSHR | |
| SCHEMBL28937988 | 0.87 | TAS2R14 (0.50) | TAS2R14NOTUMLMNAGAASMN1; SMN2 | |
| SCHEMBL45490 | 0.82 | LMNA (0.59) | NOTUMLMNAGAATSHRCFTR | |
| SCHEMBL987813 | 0.82 | TSHR (0.57) | LMNATSHRCFTRSMN1; SMN2ALDH1A1 | |
| SCHEMBL1508457 | 0.81 | LMNA (0.50) | TAS2R14NOTUMLMNAGAATSHR | |
| SCHEMBL5239843 | 0.81 | CTSS (0.51) | TAS2R14NOTUMLMNAGAATSHR | |
| SCHEMBL726068 | 0.81 | TAS2R14 (0.54) | TAS2R14NOTUMLMNAGAATSHR | |
| SCHEMBL2473776 | 0.81 | TAS2R14 (0.53) | TAS2R14NOTUMLMNAGAASMN1; SMN2 | |
| SCHEMBL31693161 | 0.81 | TAS2R14 (0.53) | TAS2R14NOTUMLMNAGAASMN1; SMN2 | |
| SCHEMBL10391427 | 0.80 | LMNA (0.45) | TAS2R14NOTUMLMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4539855-A1 | BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF | Borah, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244775-A1 | BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF | Boehringer Ingelheim Animal Health USA Inc. (US) | 2023-12-21 | — | — | WO | disclosed |