Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690792 | 0.82 | PIK3CD (0.34) | — | |
| SCHEMBL30690645 | 0.78 | IRAK4 (0.35) | IRAK4 | |
| SCHEMBL30690772 | 0.76 | PTGER4 (0.34) | IRAK4 | |
| SCHEMBL30690778 | 0.76 | PTGER4 (0.34) | IRAK4 | |
| SCHEMBL30877382 | 0.74 | PTGER4 (0.33) | — | |
| SCHEMBL30469343 | 0.73 | AAK1 (0.34) | — | |
| SCHEMBL30690780 | 0.73 | HDAC3 (0.34) | IRAK4 | |
| SCHEMBL30690687 | 0.71 | PIK3CA (0.32) | — | |
| SCHEMBL31447404 | 0.70 | AAK1 (0.33) | — | |
| SCHEMBL30877390 | 0.70 | DGAT1 (0.33) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |