Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.34 |
| ▸ | CDK2 | P24941 | 5/20 | 0.34 |
| ▸ | CCNK | O75909 | 4/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690764 | 0.81 | CHEK1 (0.39) | DGAT1PIM1 | |
| SCHEMBL30690772 | 0.79 | PTGER4 (0.34) | IRAK4DGAT1 | |
| SCHEMBL30690778 | 0.79 | PTGER4 (0.34) | IRAK4DGAT1 | |
| SCHEMBL30690669 | 0.78 | IRAK4 (0.31) | IRAK4 | |
| SCHEMBL30877441 | 0.78 | BAZ2B (0.38) | CCNA2CDK2CCNKCDK12SCN2A | |
| SCHEMBL2320459 | 0.78 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL30877382 | 0.77 | PTGER4 (0.33) | DGAT1 | |
| SCHEMBL1356777 | 0.76 | AURKA (0.33) | DGAT1 | |
| SCHEMBL30877396 | 0.76 | PGR (0.35) | CCNA2CDK2CCNKCDK12SCN2A | |
| SCHEMBL1932350 | 0.75 | NTRK1 (0.34) | DGAT1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |