Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | BTK | Q06187 | 4/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690687 | 0.88 | PIK3CA (0.32) | HDAC3HDAC2HDAC1PIK3CDPIK3CA | |
| SCHEMBL30690782 | 0.87 | ABL1 (0.32) | HDAC3HDAC2HDAC1BTKPIK3CD | |
| SCHEMBL30690781 | 0.83 | PDGFRA (0.39) | HDAC3HDAC2HDAC1ABL1 | |
| SCHEMBL30690765 | 0.82 | HRH3 (0.34) | HDAC3HDAC2HDAC1 | |
| SCHEMBL30690792 | 0.82 | PIK3CD (0.34) | PIK3CDPIK3CAMAPK1 | |
| Hydrochloric Acid SCHEMBL30690806 | 0.82 | PDGFRA (0.38) | HDAC3HDAC2HDAC1ABL1 | |
| SCHEMBL30690679 | 0.74 | PDGFRA (0.40) | HDAC3HDAC2HDAC1ABL1PIM1 | |
| SCHEMBL30690669 | 0.73 | IRAK4 (0.31) | IRAK4 | |
| SCHEMBL30690683 | 0.73 | PDGFRA (0.39) | HDAC3HDAC2HDAC1ABL1 | |
| SCHEMBL30690760 | 0.71 | CSF1R (0.40) | HDAC3HDAC2HDAC1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |