Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690778 | 1.00 | PTGER4 (0.34) | PTGER4HPGDSDGAT1NPC1MAPT | |
| SCHEMBL30877382 | 0.84 | PTGER4 (0.33) | PTGER4HPGDSDGAT1NPC1MAPT | |
| SCHEMBL25786674 | 0.84 | DGAT1 (0.35) | DGAT1NPC1MAPT | |
| SCHEMBL21115272 | 0.81 | DGAT1 (0.36) | DGAT1NPC1MAPT | |
| SCHEMBL30877390 | 0.79 | DGAT1 (0.33) | DGAT1IRAK4 | |
| SCHEMBL30690645 | 0.79 | IRAK4 (0.35) | DGAT1IRAK4 | |
| SCHEMBL27215214 | 0.78 | HPGDS (0.36) | HPGDSDGAT1IRAK4 | |
| SCHEMBL29705384 | 0.78 | HPGDS (0.36) | HPGDSDGAT1IRAK4 | |
| SCHEMBL30690630 | 0.78 | NPC1 (0.39) | DGAT1NPC1MAPT | |
| SCHEMBL1417723 | 0.77 | DGAT1 (0.39) | PTGER4HPGDSDGAT1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |