SCHEMBL30692047

CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)[C@@H](C)O)C(C)C)[C@@H](C)O

nearest known ligand 0.58

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	NPY2R	P49146	9/20	0.58

▸	NPY4R	P50391	9/20	0.58

▸	NPY5R	Q15761	9/20	0.58

▸	NPY1R	P25929	9/20	0.58

▸	NTSR1	P30989	2/20	0.53

▸	NTSR2	O95665	1/20	0.53

▸	CALCR	P30988	4/20	0.51

▸	EP300	Q09472	1/20	0.51

▸	HIF1A	Q16665	1/20	0.51

▸	F2	P00734	1/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30695264	0.92	SLC6A2 (0.52)	NPY2RNPY4RNPY5RNPY1RNTSR1
SCHEMBL31721895	0.88	CALCRL (0.53)	CALCREP300HIF1A
SCHEMBL30692048	0.86	OPRM1 (0.56)	NPY2RNPY4RNPY5RNPY1R
SCHEMBL31257916	0.86	NTSR1 (0.52)	NPY2RNPY4RNPY5RNPY1RNTSR1
SCHEMBL30607404	0.86	NPY2R (0.63)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30395647	0.85	MAPK8 (0.55)	NTSR1NTSR2CALCREP300HIF1A
SCHEMBL30607280	0.83	CALCR (0.59)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30432136	0.83	F2 (0.64)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL38660346	0.83	OPRD1 (0.62)	NPY2RNPY4RNPY5RNPY1RNTSR1
SCHEMBL30176506	0.82	NPY2R (0.63)	NPY2RNPY4RNPY5RNPY1RCALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024022465-A1	HUMAN AMYLIN POLYPEPTIDE DERIVATIVE AND USE THEREOF	杭州九源基因工程有限公司	2024-02-01	—	—	WO	disclosed