SCHEMBL30695264

SCHEMBL30695264

CC(C)C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)[C@@H](C)O)C(C)C)[C@@H](C)O

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 P23975 1/20 0.52
▸ OPRM1 P35372 1/20 0.51
▸ OPRD1 P41143 1/20 0.51
▸ REN P00797 1/20 0.51
▸ NPY2R P49146 7/20 0.50
▸ NPY4R P50391 7/20 0.50
▸ NPY5R Q15761 7/20 0.50
▸ NPY1R P25929 5/20 0.50
▸ CALCRL Q16602 2/20 0.50
▸ CALCR P30988 2/20 0.50
▸ RAMP3 O60896 1/20 0.50
▸ FCGRT P55899 2/20 0.50
▸ EP300 Q09472 1/20 0.49
▸ HIF1A Q16665 1/20 0.49
▸ NMUR2 Q9GZQ4 1/20 0.49
▸ NMUR1 Q9HB89 1/20 0.49
▸ NTSR2 O95665 1/20 0.49
▸ NTSR1 P30989 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31721895 0.96 CALCRL (0.53) OPRM1OPRD1CALCRLCALCRRAMP3
SCHEMBL30692047 0.92 NPY2R (0.58) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL29845518 0.86 REN (0.59) SLC6A2RENNTSR2NTSR1
SCHEMBL30607299 0.85 CALCR (0.57) OPRM1OPRD1NPY2RNPY4RNPY5R
SCHEMBL29404875 0.85 OPRM1 (0.63) SLC6A2OPRM1OPRD1NPY1RNMUR2
SCHEMBL30428845 0.85 OPRM1 (0.63) OPRM1OPRD1CALCRRAMP3NMUR2
SCHEMBL675630 0.84 CAPN1 (0.48) CALCRLCALCRRAMP3FCGRT
SCHEMBL31182741 0.83 CALCR (0.62) NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL31130613 0.83 CALCR (0.56) OPRM1OPRD1CALCRRAMP3NMUR2
SCHEMBL29856042 0.83 RAMP3 (0.56) SLC6A2OPRM1OPRD1NPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735021-A1 COMBINATION THERAPY Zealand Pharma A/S (DK) 2026-05-06 — — EP disclosed
EP-4731239-A1 ANALOGUES WITH IMPROVED PROPERTIES Zealand Pharma A/S (DK) 2026-04-29 — — EP disclosed
WO-2025003471-A1 COMBINATION THERAPY ZEALAND PHARMA A/S (DK) 2025-01-02 — — WO disclosed
WO-2024261076-A1 WEIGHT LOSS ZEALAND PHARMA A/S (DK) 2024-12-26 — — WO disclosed
WO-2024261259-A1 ANALOGUES WITH IMPROVED PROPERTIES ZEALAND PHARMA A/S (DK) 2024-12-26 — — WO disclosed
US-12083164-B2 Amylin analogues ZEALAND PHARMA A/S (DK) 2024-09-10 — — US disclosed
EP-4319798-A1 LIQUID FORMULATIONS OF AMYLIN ANALOGUES Zealand Pharma A/S (DK) 2024-02-14 — — EP disclosed
WO-2023232781-A1 LIQUID FORMULATIONS OF AMYLIN ANALOGUES ZEALAND PHARMA A/S (DK) 2023-12-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12083164-B2 Amylin analogues IAPP, GLP1R, AMY2A SLC6A2 828/4885OPRM1 2772/4885OPRD1 2996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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