Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30692334 | 1.00 | NPC1 (0.56) | NPC1LMNAHTTMEN1KMT2A | |
| SCHEMBL7336707 | 0.79 | LMNA (0.54) | NPC1LMNAHTTMEN1KMT2A | |
| SCHEMBL28156725 | 0.79 | NPC1 (0.47) | NPC1LMNAHTTMEN1KMT2A | |
| SCHEMBL29276646 | 0.75 | LMNA (0.59) | NPC1LMNAHTTMEN1KMT2A | |
| SCHEMBL28157284 | 0.75 | LMNA (0.44) | NPC1LMNAHTTMEN1KMT2A | |
| SCHEMBL7678596 | 0.74 | LMNA (0.88) | NPC1LMNAHTTMEN1KMT2A | |
| SCHEMBL18327174 | 0.74 | LMNA (0.89) | NPC1LMNAHTTMEN1KMT2A | |
| Salicylanilide SCHEMBL20165864 | 0.72 | MEN1 (1.00) | NPC1LMNAHTTMEN1KMT2A | |
| Salicylanilide SCHEMBL14051034 | 0.72 | MEN1 (1.00) | NPC1LMNAHTTMEN1KMT2A | |
| SCHEMBL845142 | 0.72 | LMNA (1.00) | NPC1LMNAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117045680-A | Stem cell preparation for promoting liver regeneration and preparation method thereof | 北京国卫生物科技有限公司 | 2023-11-14 | — | — | CN | disclosed |