Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 9/20 | 0.47 |
| ▸ | HTT | P42858 | 7/20 | 0.47 |
| ▸ | TP53 | P04637 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.47 |
| ▸ | PNLIP | P16233 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338425 | 0.81 | HSD17B10 (0.48) | LMNATSHRSMN1; SMN2NPC1HTT | |
| SCHEMBL30692334 | 0.79 | NPC1 (0.56) | LMNATSHRSMN1; SMN2NPC1HTT | |
| SCHEMBL30692333 | 0.79 | NPC1 (0.56) | LMNATSHRSMN1; SMN2NPC1HTT | |
| SCHEMBL28045440 | 0.75 | ALOX15 (0.64) | LMNATSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28156725 | 0.74 | NPC1 (0.47) | LMNATSHRSMN1; SMN2NPC1HTT | |
| SCHEMBL14338360 | 0.74 | TSHR (0.69) | LMNATSHRSMN1; SMN2NPC1HTT | |
| SCHEMBL14009326 | 0.73 | TP53 (0.47) | LMNATSHRSMN1; SMN2NPC1HTT | |
| Methyl Salicylate SCHEMBL29370254 | 0.72 | LMNA (1.00) | LMNATSHRSMN1; SMN2HTTKMT2A | |
| Methyl Salicylate SCHEMBL5312 | 0.72 | LMNA (1.00) | LMNATSHRSMN1; SMN2HTTKMT2A | |
| Methyl Salicylate SCHEMBL1872042 | 0.72 | LMNA (1.00) | LMNATSHRSMN1; SMN2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |